Atrophy of the cerebellar vermis in ageing. A morphometric and histologic study.

摘要: Morphometric analysis of the cerebellar vermis in 67 non-alcoholic men between 36 and 94 years age showed a significant decline Purkinje cell densities with increasing all parts vermis. However, nerve loss was much more severe superior than inferior part. There were large individual variations one-half subjects over 80 similar to those sixties. By independent evaluation, atrophy diagnosed histologically 16 cases, 13 whom 70 age. good correspondence histologic diagnoses morphometric findings. The involved 3 cortical layers changes identical seen alcoholics. diagnosis alcoholic must therefore be made great caution Cases malignant tumours had significantly lower without but same magnitude 2 groups. age-dependent seemed correlated alone not other known conditions. It probably sufficiently recognized radiologically clinically considerable number cases.