Effect of upper airway surgery on heart rate variability in patients with obstructive sleep apnoea syndrome

摘要: Summary To determine whether surgery influences cardiovascular autonomic modulation in obstructive sleep apnoea syndrome (OSAS), the present study was performed to evaluate effect of upper airway (UA) on heart rate variability (HRV) using frequency domain analysis for patient groups who have had either successful or unsuccessful surgery. We compared body mass index (BMI), polysomnographic [apnoea (AI), apnoea-hypopnoea (AHI), minimum SaO2] and HRV [very low (VLF) power, (LF) high (HF) HF/LF ratio, LFnu = LF/(LF + HF), HFnu = HF/(LF + HF)] parameters between (n = 14) (n = 22) surgical before after UA Significant changes were observed group with respect mean AI (from 29.1 ± 21.3 2.0 ± 3.2 events h−1, P < 0.001), AHI 38.6 ± 20.0 5.6 ± 5.1 events h−1, SaO2 73.3 ± 12.7 86.3 ± 6.5%, VLF power 25599 ± 12906 20014 ± 9839 ms2, P = 0.013), LF 17293 ± 7278 14155 ± 4980 ms2, P = 0.016), LFnu 0.700 ± 0.104 0.646 ± 0.128, P = 0.031) HFnu 0.300 ± 0.104 0.354 ± 0.128, P = 0.031); however, BMI, HF LF/HF ratio did not change significantly No significant group. Successful may improve cardiac sympathetic parasympathetic patients OSAS.