Nocturnal Parasympathetic Modulation of Heart Rate in Obesity-Hypoventilation Patients
作者： A. Brzecka , M. Pawelec-Winiarz , A. Teplicki , P. Piesiak , R. Jankowska
DOI: 10.1007/5584_2014_3
关键词:
摘要: Heart rate variation (HRV) reflects the activity of autonomic nervous system. The aim study was to analyze HRV in obstructive sleep apnea (OSA) and obesity hypoventilation (OH) patients answer question whether chronic alveolar influences heart regulation. In 41 patients, diagnosed with either ‘pure’ OSA (n = 23, apnea/hypopnea index – AHI: 43.8 ± 18.0 PaCO2 ≤ 45 mmHg) or OH syndrome 18, AHI 58.7 38.0 > 46 mmHg), analyzed, based on an 8 h ECG recording during sleep. compared there a globally decreased HRV, corresponding decrease high frequency power spectral analysis increased low frequency/high ratio (p < 0.05), indicating reduced parasympathetic sympathetic modulation. We conclude that hypoxemia hypercapnia disordered breathing have impact indices potential become prognostic factors for development cardiovascular complications breathing.
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