A microdialysis technique for continuous subcutaneous glucose monitoring in diabetic patients (part 1)

摘要: The performances and the stability of a novel subcutaneous glucose monitoring system have been evaluated. GlucoDay (A. Menarini I.F.R. S.r.l, Florence Italy) is portable instrument provided with micro-pump biosensor coupled to microdialysis capable recording level every 3 min. Long short term are discussed results some critical in vitro vivo (on rabbits) experiments reported. A linear response up 30 mM has found for concentration. sensitivity referred blood better than 0.1 zero current typically below equivalent mM. In accuracy study mean bias 2.7 mg/dl correlation coefficient equal 0.9697 found. At room temperature, an excellent membrane assures good 6 months from first use.