Optimization of Panax notoginseng extraction process using a design space approach

作者: Xingchu Gong , Huali Chen , Jianyang Pan , Haibin Qu

DOI: 10.1016/J.SEPPUR.2014.11.020

关键词:

摘要: … Health foods containing Panax notoginseng extract are developed in recent years. In this work, … notoginseng extract. Saponin yields and dry matter yield were identified as the process …

参考文章(33)
D.M. Barends, M.T. Oldenhof, M.J. Vredenbregt, M.J. Nauta, Risk analysis of analytical validations by probabilistic modification of FMEA Journal of Pharmaceutical and Biomedical Analysis. ,vol. 64, pp. 82- 86 ,(2012) , 10.1016/J.JPBA.2012.02.009
Lei Zhang, Binjun Yan, Xingchu Gong, Lawrence X. Yu, Haibin Qu, Application of Quality by Design to the Process Development of Botanical Drug Products: A Case Study Aaps Pharmscitech. ,vol. 14, pp. 277- 286 ,(2013) , 10.1208/S12249-012-9919-8
S.P. Li, C.F. Qiao, Y.W. Chen, J. Zhao, X.M. Cui, Q.W. Zhang, X.M. Liu, D.J. Hu, A novel strategy with standardized reference extract qualification and single compound quantitative evaluation for quality control of Panax notoginseng used as a functional food. Journal of Chromatography A. ,vol. 1313, pp. 302- 307 ,(2013) , 10.1016/J.CHROMA.2013.07.025
John J. Peterson, A Bayesian Approach to the ICH Q8 Definition of Design Space Journal of Biopharmaceutical Statistics. ,vol. 18, pp. 959- 975 ,(2008) , 10.1080/10543400802278197
Eric Rozet, Pierre Lebrun, Benjamin Debrus, Philippe Hubert, New methodology for the development of chromatographic methods with bioanalytical application. Bioanalysis. ,vol. 4, pp. 755- 758 ,(2012) , 10.4155/BIO.12.47
Xingchu Gong, Shanshan Wang, Yao Li, Haibin Qu, Separation characteristics of ethanol precipitation for the purification of the water extract of medicinal plants Separation and Purification Technology. ,vol. 107, pp. 273- 280 ,(2013) , 10.1016/J.SEPPUR.2013.01.029
Eugénia A. Macedo, António M. Peres, Thermodynamics of Ternary Mixtures Containing Sugars. SLE of d-Fructose in Pure and Mixed Solvents. Comparison between Modified UNIQUAC and Modified UNIFAC Industrial & Engineering Chemistry Research. ,vol. 40, pp. 4633- 4640 ,(2001) , 10.1021/IE0102596