Attempts to infect small laboratory animals with the infective larvae of Onchocerca lienalis.

摘要: All the natural hosts of Onchocerca parasites are large animals (MULLI-R, 1979) andthere is, therefore an urgent need to develop a small animal model for onchoccrciasis,preferably one that employs strain inbred host. Rodents have been usedsuccessfully as experimental microfilariac O. guiturosa (sec NELSON et al. 1966), cervicalis (see RAbalais, 1974), armilluta EL Bihari & Hussein, 1975) and ijibsoni Beveridge , 1980) but there few publishedattempts infect these with infective-stage larvae.