Ventricular enlargement in MS: one-year change at various stages of disease.
作者： C. M. Dalton , K. A. Miszkiel , P. W. O'Connor , G. T. Plant , G.P.A. Rice
DOI: 10.1212/01.WNL.0000201183.87175.9F
关键词:
摘要: Objectives: To investigate ventricular enlargement (VE) over 1 year at three different stages of multiple sclerosis (MS). Methods: A semi-automated technique for measuring VE was applied to MRI scans in 26 patients with clinically isolated syndromes (CIS) suggestive MS, 30 early relapse-onset MS duration, 41 established relapsing remitting (RR) and 23 secondary progressive (SP) MS. Results: seen (median increase 0.3 mL [ p = 0.003]), RRMS 0.5 0.001]), SPMS 1.1 0.001]). Allowing age there more the group ( 0.005). No observed CIS only decrease −0.001 0.829]). Significant increases T2 T1 hypointense lesion load volume were all subgroups: no differences between groups but a larger compared RRMS. Conclusions: Ventricular is sensitive measure cerebral atrophy that (MS) marked than
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