Modulation of meiotic homologous recombination by DNA helicases.

摘要: DNA helicases are ATP-driven motor proteins which translocate along capable of dismantling DNA-DNA interactions and/or removing bound to DNA. These biochemical capabilities make main regulators crucial metabolic processes, including replication, repair, and genetic recombination. This budding topic will focus on reviewing the function important for homologous recombination during meiosis, discuss recent advances in how these modulators meiotic themselves regulated. The emphasis is placed work two model yeasts, Saccharomyces cerevisiae Schizosaccharomyces pombe, has vastly expanded our understanding recombination, a process whose correct execution instrumental healthy gamete formation, thus functioning sexual reproduction. article protected by copyright. All rights reserved.