Reversal of Lower-Extremity Intermittent Claudication and Rest Pain by Hydration.

摘要: Background Medical treatment of disabling intermittent claudication or critical limb-threatening ischemia causing rest pain often fails has partial response. Methods In this pilot study, 36 patients (12 females) affected by the lower extremities were exposed to a daily 3-L water intake for up 6 weeks. Cutaneous foot temperature, ankle/brachial index, time and distance claudication, intensity recorded before at completion hydration period. Results Patients with mean ± SE age 71 ± 2 years (range, 40–86) had (less than 100 meters) more 5 months while 11% reported rest. A 6-week 2,500 mL/24 hr was achieved in 35 enrolled study. Increased associated significant improvements median index (from 0.60 0.76; P Conclusions This study suggests that attained consumption 2.5 L robust impact on reducing symptoms caused peripheral vascular disease.