Late survival of non-small cell lung cancer patients with brain metastases. Influence of treatment.

摘要: The presence of brain metastasis in lung cancer patients is a highly unfavorable event that usually allows only palliative treatment. A retrospective study was conducted to evaluate the prognostic factors with non-small cell (NSCLC) associated metastases. From July 1984 through June 1990, total 50 NSCLC symptomatic seen at National Taiwan University Hospital were included. Patients who had incomplete staging workup or loss follow-up excluded. Several possible variables analyzed initially univariate analysis and subsequently multivariate maximal partial likelihood ratio test Cox model. In analysis, several factors, including number metastases, treatment for tumor resection (BTR) whole radiation therapy (WBRT), chemotherapy (C/T) after found have significant influence on survival. However, receiving BTR, WBRT, and/or C/T lived significantly longer. median survival treated BTR nine months, eight months C/T, seven WBRT. Taken together, these which longer than supportive care (with two months). Treatment metastases combinations also improved quality life. We conclude should be more aggressively only.