p53 regulates biosynthesis through direct inactivation of glucose-6-phosphate dehydrogenase

作者: Peng Jiang , Wenjing Du , Xingwu Wang , Anthony Mancuso , Xiang Gao

DOI: 10.1038/NCB2172

关键词:

摘要: … The p53 protein binds to glucose-6-phosphate dehydrogenase (G6PD), the first and rate-limiting enzyme of the PPP, and prevents the formation of the active dimer. Tumour-associated …

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