Measuring red blood cell flow dynamics in a glass capillary using Doppler optical coherence tomography and Doppler amplitude optical coherence tomography.
作者： Julian Moger , Stephen J. Matcher , C. Peter Winlove , Angela Shore
DOI: 10.1117/1.1781163
关键词:
摘要: Blood, being a suspension of deformable red cells suspended in plasma, displays flow dynamics considerably more complicated than those an ideal Newtonian fluid. Flow blood capillaries few hundred micrometers diameter are investigated using Doppler optical coherence tomography (DOCT) and amplitude (DAOCT), novel extension DOCT. Velocity profiles concentration distributions normal rigidified vitro cell suspensions shown to vary as functions mean velocity, concentration, rigidity. Deviation from the parabolic velocity profile expected for Pouseille is observed both rigid at low rates. Axial migration toward away tube axis function velocity. Good agreement found between our measurements, theoretical expectations.
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sci-hub.se 参考文章(11)
Ton G. van Leeuwen, Manish D. Kulkarni, Siavash Yazdanfar, Andrew M. Rollins, Joseph A. Izatt, High-flow-velocity and shear-rate imaging by use of color Doppler optical coherence tomography. Optics Letters. ,vol. 24, pp. 1584- 1586 ,(1999) , 10.1364/OL.24.001584
Zhongping Chen, Thomas E. Milner, Digant Dave, J. Stuart Nelson, Optical Doppler tomographic imaging of fluid flow velocity in highly scattering media. Optics Letters. ,vol. 22, pp. 64- 66 ,(1997) , 10.1364/OL.22.000064
G. J. Tearney, B. E. Bouma, J. G. Fujimoto, High-speed phase- and group-delay scanning with a grating-based phase control delay line. Optics Letters. ,vol. 22, pp. 1811- 1813 ,(1997) , 10.1364/OL.22.001811
Zhongping Chen, Thomas E. Milner, Xiaojun Wang, Shyam Srinivas, J. Stuart Nelson, Optical Doppler Tomography: Imaging in vivo Blood Flow Dynamics Following Pharmacological Intervention and Photodynamic Therapy Photochemistry and Photobiology. ,vol. 67, pp. 56- 60 ,(1998) , 10.1111/J.1751-1097.1998.TB05165.X
Julian Moger, Stephen J. Matcher, Peter Winlove, Angel C. Shore, Measuring blood flow dynamics using DOCT and Doppler amplitude optical coherence tomography (DAOCT) Biomedical optics. ,vol. 4956, pp. 366- 373 ,(2003) , 10.1117/12.477639
G Michelson, B Schmauss, Two dimensional mapping of the perfusion of the retina and optic nerve head. British Journal of Ophthalmology. ,vol. 79, pp. 1126- 1132 ,(1995) , 10.1136/BJO.79.12.1126
Joseph A. Izatt, Manish D. Kulkarni, Siavash Yazdanfar, Jennifer K. Barton, Ashley J. Welch, In vivo bidirectional color Doppler flow imaging of picoliter blood volumes using optical coherence tomography. Optics Letters. ,vol. 22, pp. 1439- 1441 ,(1997) , 10.1364/OL.22.001439
J. M. Schmitt, A. Knüttel, R. F. Bonner, Measurement of optical properties of biological tissues by low-coherence reflectometry Applied Optics. ,vol. 32, pp. 6032- 6042 ,(1993) , 10.1364/AO.32.006032
Zhongping Chen, Thomas E. Milner, Shyam Srinivas, Xiaojun Wang, Arash Malekafzali, Martin J. C. van Gemert, J. Stuart Nelson, Noninvasive imaging of in vivo blood flow velocity using optical Doppler tomography Optics Letters. ,vol. 22, pp. 1119- 1121 ,(1997) , 10.1364/OL.22.001119
Andrew M. Rollins, Siavash Yazdanfar, Jennifer K. Barton, Joseph A. Izatt, Real-time in vivo color Doppler optical coherence tomography Journal of Biomedical Optics. ,vol. 7, pp. 123- 129 ,(2002) , 10.1117/1.1428291