Silicon dioxide surfaces with aryl interaction sites for chromatographic applications
作者： R. Gadzała-Kopciuch , M. Kluska , M. Wełniak , B. Buszewski
DOI: 10.1016/J.MATCHEMPHYS.2004.03.022
关键词:
摘要: The paper presents the results of a study on aryl phases aimed at increase separation selectivity substances containing π electrons, and improving reproducibility retention data. above contain not only carbon chain different length, linking them to support, but also one or two aromatic rings. suitability newly obtained packings for purposes high-performance liquid chromatography was verified basis description surface topography before after modification process. Various physicochemical methods were employed determine effectiveness chemical modification, i.e., elemental analysis, infrared spectroscopy, nuclear magnetic resonance. used polynuclear hydrocarbons budesonide epimers, tested under hydroorganic conditions (water/ethanol, water/methanol, water/acetonitrile). application methanol/water mobile phase new-generation naphthylpropyl stationary 22R 22S diastereoisomers allowed obtention reproducible make qualitative quantitative determinations particular enantiomers.
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sci-hub.se 参考文章(45)
Wolfram Wielandt, Arndt Ellwanger, Klaus Albert, Ekkehard Lindner, n-alkyl fluorenyl phases in chromatography. I. Synthesis and characterization. Journal of Chromatography A. ,vol. 805, pp. 71- 83 ,(1998) , 10.1016/S0021-9673(98)00014-4
R.A. Thompson, S. Andersson, S. Allenmark, Direct liquid chromatographic separation of enantiomers on immobilized protein stationary phases Journal of Chromatography A. ,vol. 465, pp. 263- 270 ,(1989) , 10.1016/S0021-9673(01)92664-0
Pavel Jandera, Reversed-phase liquid chromatography of homologous series : A general method for prediction of retention Journal of Chromatography A. ,vol. 314, pp. 13- 36 ,(1984) , 10.1016/S0021-9673(01)97720-9
G. A. Howard, A. J. P. Martin, The separation of the C12-C18 fatty acids by reversed-phase partition chromatography Biochemical Journal. ,vol. 46, pp. 532- 538 ,(1950) , 10.1042/BJ0460532
Matthias Pursch, Lane C. Sander, Klaus Albert, Chain Order and Mobility of High-Density C18 Phases by Solid-State NMR Spectroscopy and Liquid Chromatography Analytical Chemistry. ,vol. 68, pp. 4107- 4113 ,(1996) , 10.1021/AC9606113
Gert E. Berendsen, Leo De Galan, Role of the chain length of chemically bonded phases and the retention mechanism in reversed-phase liquid chromatography Journal of Chromatography A. ,vol. 196, pp. 21- 37 ,(1980) , 10.1016/S0021-9673(00)80356-8
Rainer Brindle, Klaus Albert, Stationary phases with chemically bonded fluorene ligands: A new approach for environmental analysis of π-electron containing solutes Journal of Chromatography A. ,vol. 757, pp. 3- 20 ,(1997) , 10.1016/S0021-9673(96)00682-6
William H. Pirkle, Thomas C. Pochapsky, Considerations of chiral recognition relevant to the liquid chromatography separation of enantiomers Chemical Reviews. ,vol. 89, pp. 347- 362 ,(1989) , 10.1021/CR00092A006
P. Roumeliotis, K.K. Unger, Structure and properties ofn-alkyldimethylsilyl bonded silica reversed-phase packings Journal of Chromatography A. ,vol. 149, pp. 211- 224 ,(1978) , 10.1016/S0021-9673(00)80987-5
Junior E. Sandoval, Joseph J. Pesek, Hydrolytically stable bonded chromatographic phases prepared through hydrosilation of olefins on a hydride-modified silica intermediate Analytical Chemistry. ,vol. 63, pp. 2634- 2641 ,(1991) , 10.1021/AC00022A017