The multistep nature of cancer.
作者： Bert Vogelstein , Kenneth W. Kinzler
DOI: 10.1016/0168-9525(93)90209-Z
关键词:
摘要: Cancer is a distinct type of genetic disease in which not one, but several, mutations are required. Each mutation drives a wave of cellular multiplication associated with gradual …
elsevier.com
sci-hub.se 参考文章(24)
Wendy H. Raskind, Philip J. Fialkow, The Use of Cell Markers in The Study of Human Hematopoietic Neoplasia Advances in Cancer Research. ,vol. 49, pp. 127- 167 ,(1987) , 10.1016/S0065-230X(08)60796-4
M C Goyette, K Cho, C L Fasching, D B Levy, K W Kinzler, C Paraskeva, B Vogelstein, E J Stanbridge, Progression of colorectal cancer is associated with multiple tumor suppressor gene defects but inhibition of tumorigenicity is accomplished by correction of any single defect via chromosome transfer. Molecular and Cellular Biology. ,vol. 12, pp. 1387- 1395 ,(1992) , 10.1128/MCB.12.3.1387
H Land, A C Chen, J P Morgenstern, L F Parada, R A Weinberg, Behavior of myc and ras oncogenes in transformation of rat embryo fibroblasts. Molecular and Cellular Biology. ,vol. 6, pp. 1917- 1925 ,(1986) , 10.1128/MCB.6.6.1917
Eric Sinn, William Muller, Paul Pattengale, Isidore Tepler, Racheal Wallace, Philip Leder, Coexpression of MMTV/v-Ha-ras and MMTV/c-myc genes in transgenic mice: Synergistic action of oncogenes in vivo Cell. ,vol. 49, pp. 465- 475 ,(1987) , 10.1016/0092-8674(87)90449-1
P. Nowell, The clonal evolution of tumor cell populations Science. ,vol. 194, pp. 23- 28 ,(1976) , 10.1126/SCIENCE.959840
KW Kinzler, I Nishisho, Y Nakamura, Y Miyoshi, Y Miki, H Ando, A Horii, K Koyama, J Utsunomiya, S Baba, P Hedge, A Markham, AJ Krush, G Petersen, SR Hamilton, MC Nilbert, DB Levy, TM Bryan, AC Preisinger, KJ Smith, LK Su, B Vogelstein, Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients Science. ,vol. 253, pp. 665- 669 ,(1991) , 10.1126/SCIENCE.1651563
Joanna Groden, Andrew Thliveris, Wade Samowitz, Mary Carlson, Lawrence Gelbert, Hans Albertsen, Geoff Joslyn, Jeff Stevens, Lisa Spirio, Margaret Robertson, Leslie Sargeant, Karen Krapcho, Erika Wolff, Randall Burt, J.P. Hughes, Janet Warrington, John McPherson, John Wasmuth, Denis Le Paslier, Hadi Abderrahim, Daniel Cohen, Mark Leppert, Ray White, Identification and characterization of the familial adenomatous polyposis coli gene Cell. ,vol. 66, pp. 589- 600 ,(1991) , 10.1016/0092-8674(81)90021-0
J. Adams, S Cory, Transgenic models of tumor development Science. ,vol. 254, pp. 1161- 1167 ,(1991) , 10.1126/SCIENCE.1957168
Eric R. Fearon, Bert Vogelstein, A genetic model for colorectal tumorigenesis Cell. ,vol. 61, pp. 759- 767 ,(1990) , 10.1016/0092-8674(90)90186-I
Daniel E Epner, H Phillip Koeffler, Molecular Genetic Advances in Chronic Myelogenous Leukemia Annals of Internal Medicine. ,vol. 113, pp. 3- 6 ,(1990) , 10.7326/0003-4819-113-1-3