Sn-chlorin e6 antibacterial immunoconjugates. An in vitro and in vivo analysis.

作者: Lu Xiao-Ming , Alan J. Fischman , Emily Stevens , Thomas T. Lee , Louis Strong

DOI: 10.1016/0022-1759(92)90014-K

关键词:

摘要: Monoclonal antibody-Sn-chlorin e6 immunoconjugates were … groups as axial ligands of the Sn moiety, conjugates with in vivo … yields than that observed with the Sn-chlorin e6 precursor …

参考文章(47)
Eric M. Morrel, Ronald G. Tompkins, Alan J. Fischman, Robert A. Wilkinson, Martin L. Yarmush, Imaging infections with antibodies. A quantitative autoradiographic analysis. Journal of Immunological Methods. ,vol. 130, pp. 39- 48 ,(1990) , 10.1016/0022-1759(90)90297-9
Tarun I. Ghose, A. Huntley Blair, Padmaja N. Kulkarni, [20] Preparation of antibody-linked cytotoxic agents Immunochemical Techniques Part F: Conventional Antibodies, Fc Receptors, and Cytotoxicity. ,vol. 93, pp. 280- 333 ,(1983) , 10.1016/S0076-6879(83)93050-1
PAOLO Di MASCIO, THOMAS P. A. DEVASAGAYAM, STEPHAN KAISER, HELMUT SIES, Carotenoids, tocopherols and thiols as biological singlet molecular oxygen quenchers. Biochemical Society Transactions. ,vol. 18, pp. 1054- 1056 ,(1990) , 10.1042/BST0181054
G H Towers, C K Wat, D Mew, J G Levy, Photoimmunotherapy: treatment of animal tumors with tumor-specific monoclonal antibody-hematoporphyrin conjugates. Journal of Immunology. ,vol. 130, pp. 1473- 1477 ,(1983)
JOSEPH S. FRIEDBERG, RONALD G. TOMPKINS, SCOTT L. RAKESTRAW, STEPHEN W. WARREN, ALAN J. FISCHMAN, MARTIN L. YARMUSH, Antibody-targeted photolysis. Bacteriocidal effects of Sn (IV) chlorin e6-dextran-monoclonal antibody conjugates. Annals of the New York Academy of Sciences. ,vol. 618, pp. 383- 393 ,(1991) , 10.1111/J.1749-6632.1991.TB27258.X
Frank Rizzuto, John D. Spikes, The eosin-sensitized photooxidation of substituted phenylalanines and tyrosines. Photochemistry and Photobiology. ,vol. 25, pp. 465- 476 ,(1977) , 10.1111/J.1751-1097.1977.TB09172.X
J. D. Rodwell, V. L. Alvarez, C. Lee, A. D. Lopes, J. W. Goers, H. D. King, H. J. Powsner, T. J. McKearn, Site-specific covalent modification of monoclonal antibodies: in vitro and in vivo evaluations Proceedings of the National Academy of Sciences of the United States of America. ,vol. 83, pp. 2632- 2636 ,(1986) , 10.1073/PNAS.83.8.2632
Scott L. Rakestraw, William E. Ford, Ronald G. Tompkins, Michael A. J. Rodgers, William P. Thorpe, Martin L. Yarmush, Antibody‐Targeted Photolysis: In Vitro Immunological, Photophysical, and Cytotoxic Properties of Monoclonal Antibody‐Dextran‐Sn(IV) Chlorin e6 Immunoconjugates Biotechnology Progress. ,vol. 8, pp. 30- 39 ,(1992) , 10.1021/BP00013A006
Lisa Beewen Shih, Robert M. Sharkey, F. James Primus, David M. Goldenberg, Site-specific linkage of methotrexate to monoclonal antibodies using an intermediate carrier. International Journal of Cancer. ,vol. 41, pp. 832- 839 ,(1988) , 10.1002/IJC.2910410610