Hypofractionated Radiation Therapy in the Treatment of Early-Stage Breast Cancer
作者： Gary M. Freedman
DOI: 10.1007/S11912-011-0207-7
关键词:
摘要: Hypofractionated radiation refers to the use of fewer, larger-dose treatments that are usually given over a shorter time period compared conventional fraction sizes. Randomized trials hypofractionated whole breast irradiation (WBI) have demonstrated comparable outcomes as fractionation. For higher-risk population for local recurrence, phase 3 trial by Radiation Therapy Oncology Group (RTOG) is currently studying WBI with concurrent tumor bed boost weeks. Accelerated partial limits region 1–3 weeks and subject an ongoing randomized National Surgical Breast Bowel Project RTOG. Questions remain hypofractionation about optimal patient selection, techniques, risk late toxicity. But results from current could make more widely accepted patients early-stage cancer.
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sci-hub.se 参考文章(50)
Robert W Carlson, BO Anderson, W Bensinger, CE Cox, NE Davidson, SB Edge, William Blair Farrar, LJ Goldstein, WJ Gradishar, AS Lichter, B McCormick, LM Nabell, EC Reed, SM Silver, ML Smith, G Somlo, R Theriault, JH Ward, EP Winer, A Wolff, None, NCCN Practice Guidelines for Breast Cancer. Oncology. ,vol. 14, pp. 33- 49 ,(2000)
博志 山口, What's going on 乳癌 Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: an overview of the randomised trials. Clarke M, et al; Early Breast Cancer Trialists' Collaborative Group(EBCTCG). Lancet. 2005; 366: 2087-106. PMID: 16360786--乳房温存または乳房切除術後に行う放射線治療は局所再発を有意に抑制するが、長期予後も改善することができることを明らかにした論文 Mebio oncology. ,vol. 3, pp. 106- 110 ,(2006)
The UK Standardisation of Breast Radiotherapy (START) Trial B of radiotherapy hypofractionation for treatment of early breast cancer: a randomised trial. The Lancet. ,vol. 371, pp. 1098- 1107 ,(2008) , 10.1016/S0140-6736(08)60348-7
Gary M Freedman, Penny R Anderson, Lori J Goldstein, Chang-Ming Ma, Jinsheng Li, Ramona F Swaby, Samuel Litwin, Deborah Watkins-Bruner, Elin R Sigurdson, Monica Morrow, None, Four-week course of radiation for breast cancer using hypofractionated intensity modulated radiation therapy with an incorporated boost. International Journal of Radiation Oncology Biology Physics. ,vol. 68, pp. 347- 353 ,(2007) , 10.1016/J.IJROBP.2006.12.035
Peter Y. Chen, Michelle Wallace, Christina Mitchell, Inga Grills, Larry Kestin, Ashley Fowler, Alvaro Martinez, Frank Vicini, Four-year efficacy, cosmesis, and toxicity using three-dimensional conformal external beam radiation therapy to deliver accelerated partial breast irradiation. International Journal of Radiation Oncology Biology Physics. ,vol. 76, pp. 991- 997 ,(2010) , 10.1016/J.IJROBP.2009.03.012
T.B. Julian, J.P. Costantino, F.A. Vicini, J.R. White, K.A. Winter, D.W. Arthur, R.R. Kuske, R. Rabinovitch, W.J. Curran, N. Wolmark, Early Toxicity Results with 3-D Conformal External Beam Therapy (CEBT) from the NSABP B-39/RTOG 0413 Accelerated Partial Breast Irradiation (APBI) Trial International Journal of Radiation Oncology*Biology*Physics. ,vol. 81, pp. S7- ,(2011) , 10.1016/J.IJROBP.2011.06.014
David E. Wazer, Seth Kaufman, Laurie Cuttino, Thomas DiPetrillo, Douglas W. Arthur, Accelerated partial breast irradiation: An analysis of variables associated with late toxicity and long-term cosmetic outcome after high-dose-rate interstitial brachytherapy International Journal of Radiation Oncology Biology Physics. ,vol. 64, pp. 489- 495 ,(2006) , 10.1016/J.IJROBP.2005.06.028
Anthony E. Dragun, Jennifer L. Harper, Joseph M. Jenrette, Debajyoti Sinha, David J. Cole, Predictors of cosmetic outcome following MammoSite breast brachytherapy: a single-institution experience of 100 patients with two years of follow-up. International Journal of Radiation Oncology Biology Physics. ,vol. 68, pp. 354- 358 ,(2007) , 10.1016/J.IJROBP.2006.12.014
Gary M. Freedman, Penny R. Anderson, Alexandra L. Hanlon, Debra F. Eisenberg, Nicos Nicolaou, Pattern of local recurrence after conservative surgery and whole-breast irradiation International Journal of Radiation Oncology Biology Physics. ,vol. 61, pp. 1328- 1336 ,(2005) , 10.1016/J.IJROBP.2004.08.026
Frank Vicini, Kathryn Winter, John Wong, Helen Pass, Rachel Rabinovitch, Susan Chafe, Douglas Arthur, Ivy Petersen, Julia White, Beryl McCormick, Initial Efficacy Results of RTOG 0319: Three-Dimensional Conformal Radiation Therapy (3D-CRT) Confined to the Region of the Lumpectomy Cavity for Stage I/ II Breast Carcinoma International Journal of Radiation Oncology Biology Physics. ,vol. 77, pp. 1120- 1127 ,(2008) , 10.1016/J.IJROBP.2009.06.067