Synthesis and characterization of intrinsically radiolabeled lanthanide phosphate nanoparticles toward biomedical and environmental applications

作者: M. Toro-González , D. M. Clifford , R. Copping , S. Mirzadeh , J. V. Rojas

DOI: 10.1007/S11051-018-4338-8

关键词:

摘要: Lanthanide phosphate nanomaterials are appealing as multifunctional platforms for biomedical applications because of their low toxicity, radiation resistance, and unique luminescence magnetic properties. nanoparticles (NPs) radiolabeled with 156Eu were synthesized by an aqueous route using sodium tripolyphosphate a source complexing agent. GdPO4 was used host matrix, while synthetic concentrations Ce3+/Tb3+ Eu3+ varied between 5–40% 10–30%, respectively, yielded spherical NPs hexagonal crystal system particle size  90% achieved Gd0.6Ce0.3Tb0.1PO4 intrinsically 156Eu. In vitro retention within LnPO4 > 97% over 3 weeks. Intrinsically have the potential to combine properties Ln3+ ions lanthanide radioisotopes environmental applications.

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