Intracranial Phycomycosis" A Clinicopathological and Radiological Study

摘要: Abstract In 3 patients with diabetes mellitus and ketoacidosis one uremia from chronic renal disease, phycomycotic infection extended into the intracranial cavity paranasal sinuses, leading to death in all 4 cases. Striking angiographic changes occurred cases, consisting of irregular narrowings arteries, at times stenosis or occlusion, 1 case, findings indicative a mycotic aneurysm. The clinical radiographic could be correlated pathological carotid arteries their branches, which resulted invasion destruction arterial wall by fungus. This turn led thrombus formation infarction brain tissue, either directly as result embolization; aneurysm was consequence distinctive alteration internal artery. cases biopsy specimens showed presence fungus class Phycomycetes . 3, organisms were identified culture belonging genus Rhizopus family Mucoraceae Treatment amphotericin B may have inhibited growth but ineffective controlling any