Patients with Adenocarcinoma of the Small Intestine with 9 or More Regional Lymph Nodes Retrieved Have a Higher Rate of Positive Lymph Nodes and Improved Survival

摘要: To assess the influence of regional lymph node (RLN) retrieval on stage migration adenocarcinoma small intestine and survival. From Surveillance, Epidemiology, End Results database,1090 patients with nonmetastatic bowel were identified in between 2004 2011. The impact number RLNs removed histopathological staging oncological outcome was assessed utilizing Cox proportional hazard regression models without risk-adjustment, propensity score methods, joinpoint analysis. rate node-positive cancer increased steadily retrieved up to 9 RLNs, which suggests that a minimum (95 % CI 5.5–10.5) are needed for detection disease (P < 0.001). 657 1090 (60.3 %), or more retrieved. While only 46.0 % all cases 9+ retrieved, this 69.3 % 2011 multivariable analysis demonstrated associated better overall (hazard ratio death [HR] = 0.67, 95 % 0.55–0.82, P < 0.001) cancer-specific survival (HR = 0.77, 0.61–0.96, P = 0.022). This finding confirmed by score-adjusted analysis, indicated (HR = 0.67, 0.50–0.89, 0.49–0.92, P = 0.013) RLNs. our knowledge, is first population-based investigation adenocarcinoma. A sufficient should be achieve an optimal outcome.