Stabilization of β-Catenin by Genetic Defects in Melanoma Cell Lines

作者: B. Rubinfeld

DOI: 10.1126/SCIENCE.275.5307.1790

关键词:

摘要: … antibody to rabbit immunoglobin G (IgG) (Sigma). We detected β-catenin by using mouse anti-β-catenin monoclonal antibody (… donkey antibody to mouse IgG (Cappel, Durham, NC). …

参考文章(19)
B Gumbiner, Signal transduction of beta-catenin. Current Opinion in Cell Biology. ,vol. 7, pp. 634- 640 ,(1995) , 10.1016/0955-0674(95)80104-9
S L Topalian, S A Rosenberg, D Solomon, Tumor-specific cytolysis by lymphocytes infiltrating human melanomas. Journal of Immunology. ,vol. 142, pp. 3714- 3725 ,(1989)
Susan Munemitsu, Brian Souza, Oliver Müller, Iris Albert, Paul Polakis, Bonnee Rubinfeld, The APC Gene Product Associates with Microtubules in Vivo and Promotes Their Assembly in Vitro Cancer Research. ,vol. 54, pp. 3676- 3681 ,(1994)
D. E. Brash, J. A. Rudolph, J. A. Simon, A. Lin, G. J. McKenna, H. P. Baden, A. J. Halperin, J. Ponten, A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 88, pp. 10124- 10128 ,(1991) , 10.1073/PNAS.88.22.10124
Jürgen Behrens, Jens P. von Kries, Michael Kühl, Laurakay Bruhn, Doris Wedlich, Rudolf Grosschedl, Walter Birchmeier, Functional interaction of β-catenin with the transcription factor LEF-1 Nature. ,vol. 382, pp. 638- 642 ,(1996) , 10.1038/382638A0
C Yost, M Torres, J R Miller, E Huang, D Kimelman, R T Moon, The axis-inducing activity, stability, and subcellular distribution of beta-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3. Genes & Development. ,vol. 10, pp. 1443- 1454 ,(1996) , 10.1101/GAD.10.12.1443
Otmar Huber, Reinhard Korn, John McLaughlin, Mami Ohsugi, Bernhard G. Herrmann, Rolf Kemler, Nuclear localization of β-catenin by interaction with transcription factor LEF-1 Mechanisms of Development. ,vol. 59, pp. 3- 10 ,(1996) , 10.1016/0925-4773(96)00597-7
R S Bradley, P Cowin, A M Brown, Expression of Wnt-1 in PC12 cells results in modulation of plakoglobin and E-cadherin and increased cellular adhesion. Journal of Cell Biology. ,vol. 123, pp. 1857- 1865 ,(1993) , 10.1083/JCB.123.6.1857
Ann S. Tsukamoto, Rudolf Grosschedl, Raphael C. Guzman, Tristram Parslow, Harold E. Varmus, Expression of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice. Cell. ,vol. 55, pp. 619- 625 ,(1988) , 10.1016/0092-8674(88)90220-6
Mark Peifer, Cell adhesion and signal transduction: the Armadillo connection Trends in Cell Biology. ,vol. 5, pp. 224- 229 ,(1995) , 10.1016/S0962-8924(00)89015-7