Sources of Folate and Serum Folate Levels in Older Adults
作者： Jessica E. Mulligan , Geoffrey W. Greene , Marjorie Caldwell
DOI: 10.1016/J.JADA.2006.12.001
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摘要: Abstract This study examined dietary folate intake in 173 older adults. A subsample (n=128) also provided data about folic acid from vitamin/mineral supplements and serum folate. Subjects were community-dwelling men women 60 years of age older. Overall, this sample had healthful patterns with adequate Mean converted to equivalents (DFE) was 464 μg DFE/day. However, 20% (n=36) inadequate 2% (n=3) high DFE (>1,000 DFE/day). completed a supplement questionnaire biochemical assessment Adding (total DFE), increased 766 DFE/day; 13% (n=16) inadequate, 75% (n=95) adequate, (n=13) total DFE. No subject low reported use, but 94% (n=39) did so. In the subsample, all subjects acceptable levels (mean folate=28.0±13.8 ng/mL [63.5±31.3 nmol/L]). conclusion, should be included nutrition Older adults may at risk for if their energy is low, they do not take supplement, or are consuming fortified cereals. excess consume both
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John D. Potter, Food, nutrition and the prevention of cancer : a global perspective Published in <b>1997</b> in Washington DC by World Cancer Research Fund. ,(1997)
C.J. Lammi-Keefe, J. Haller, M. Ferry, R.M. Weggemans, Changes in the vitamin status of elderly Europeans: plasma vitamins A, E, B-6, B-12, folic acid and carotenoids. European Journal of Clinical Nutrition. ,vol. 50, ,(1996)
Diane L. McKay, Gayle Perrone, Helen Rasmussen, Gerard Dallal, Jeffrey B. Blumberg, Multivitamin/mineral supplementation improves plasma B-vitamin status and homocysteine concentration in healthy older adults consuming a folate-fortified diet. Journal of Nutrition. ,vol. 130, pp. 3090- 3096 ,(2000) , 10.1093/JN/130.12.3090
Shirley A. A. Beresford, Arno G. Motulksy, Homocysteine, Folic Acid, and Cardiovascular Disease Risk Humana Press. pp. 191- 219 ,(2005) , 10.1007/978-1-59259-880-9_8
Bruce N. Ames, DNA damage from micronutrient deficiencies is likely to be a major cause of cancer. Mutation Research. ,vol. 475, pp. 7- 20 ,(2001) , 10.1016/S0027-5107(01)00070-7
Jacob Selhub, Paul F. Jacques, Irwin H. Rosenberg, Gail Rogers, Barbara A. Bowman, Elaine W. Gunter, Jacqueline D. Wright, Clifford L. Johnson, Serum Total Homocysteine Concentrations in the Third National Health and Nutrition Examination Survey (1991–1994): Population Reference Ranges and Contribution of Vitamin Status to High Serum Concentrations Annals of Internal Medicine. ,vol. 131, pp. 331- 339 ,(1999) , 10.7326/0003-4819-131-5-199909070-00003
Shumin Zhang, David J Hunter, Susan E Hankinson, Edward L Giovannucci, Bernard A Rosner, Graham A Colditz, Frank E Speizer, Walter C Willett, A Prospective Study of Folate Intake and the Risk of Breast Cancer JAMA. ,vol. 281, pp. 1632- 1637 ,(1999) , 10.1001/JAMA.281.17.1632
Joel G. Ray, David E.C. Cole, Sheila C. Boss, An Ontario-wide study of vitamin B12, serum folate, and red cell folate levels in relation to plasma homocysteine: is a preventable public health issue on the rise? Clinical Biochemistry. ,vol. 33, pp. 337- 343 ,(2000) , 10.1016/S0009-9120(00)00083-7
Dieneke Z. van Asselt, Wim J. van den Broek, Cornelis B. Lamers, Frans H. Corstens, Willibrord H. Hoefnagels, Free and Protein‐Bound Cobalamin Absorption in Healthy Middle‐aged and Older Subjects Journal of the American Geriatrics Society. ,vol. 44, pp. 949- 953 ,(1996) , 10.1111/J.1532-5415.1996.TB01866.X
Silvina F. Choumenkovitch, Paul F. Jacques, Marie R. Nadeau, Peter W. F. Wilson, Irwin H. Rosenberg, Jacob Selhub, Folic Acid Fortification Increases Red Blood Cell Folate Concentrations in the Framingham Study Journal of Nutrition. ,vol. 131, pp. 3277- 3280 ,(2001) , 10.1093/JN/131.12.3277