Hypercortisolism and obesity.

摘要: Obesity is a multifactorial heterogenous condition. The location of excess fat on the body determines risk morbidity and mortality for significant disease. Visceral, or intraabdominal, depot most highly associated with illness death from cardiocerebrovascular disease diabetes. Visceral also quartet metabolic disturbances. Referred to as syndrome, these abnormalities include hypertension, hyperlipidemia, hyperinsulinemia, insulin resistance. syndrome present in Cushing's which characterized by primary hypercortisolism well profound visceral adiposity obesity. interrelationship between hyperactivation hypersensitivity stress axis can be elucidated an understanding effect glucocorticoids upon energy storage metabolism. complex interactions growth reproductive axes, adipose tissue, suggest that chronic stress, whether psychological and/or physical, exerts intense composition, which, turn, significantly affects longevity survival organism.