Antibodies to Tamm-Horsfall protein associated with renal damage and urinary tract infections in adults

作者: Anders Fasth , Ulla Bengtsson , Bertil Kaijser , Jan Wieslander

DOI: 10.1038/KI.1981.167

关键词:

摘要: Autoantibodies to Tamm-Horsfall protein associated with renal damage and urinary tract infections in adults. Forty-seven adults infection (UTI), 9 recent acute pyelonephritis 38 previous infection, were investigated for the presence of autoantibodies (THP). All patients except 6 had or vesicoureteric reflux (VUR). In pyelonephritis, only IgA antibodies significantly elevated. Among UTI, more than months before time testing, a graded response was found IgG IgM specific antibodies, lowest value those elevated serum creatinine highest normal X-ray. A negative correlation between THP (r = -0.76, P Auto-anticorps anti-proteine de associes des lesions renales et urinaires chez l'adulte Quarante-sept adultes atteints d'infection urinaire, ayant une pyelonephrite aigue recente renale anterieure ont ete etudies pour la d'auto-anticorps Tous les malades sauf six avaient ou eu un vesico-ureteral. Chez antecedent seul anti-corps etaient significativement eleves. Parmi dont l'antecedent urinaire remontait plus mois reponse obtenue specifiques IgM, avec valeur faible ceux qui creatininemie elevee indemnes radiologiques. Une observee entre anti l'augmentation -0,76,

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