Regeneration of the sciatic nerve in rats. The effect of muscle basement membrane
作者： MA Glasby , S Gschmeissner , RJ Hitchcock , CL Huang , None
DOI: 10.1302/0301-620X.68B5.3782256
关键词:
摘要: An orientated substratum has been implicated in the development and regeneration of axons synapses. We prepared a basement membrane matrix from autogenous striated muscle, used it to repair sciatic nerve rats, then investigated results by histology electrophysiology. When treated grafts were coaxially aligned with fascicles functional recovery appeared within 30 days, good growth into distal nerve. Grafts myotubes at right angles supported but slower rate. untreated muscle allowed axon penetration only through naturally degenerated fibres, minimal It is concluded that rat graft correctly empty can facilitate guide peripheral after injury so lead recolonisation stump recovery.
sci-hub.se 参考文章(15)
W. Holmes, J. Z. Young, Nerve regeneration after immediate and delayed suture. Journal of Anatomy. ,vol. 77, pp. 63- ,(1942)
F. K. Sanders, J. Z. Young, The degeneration and re-innervation of grafted nerves. Journal of Anatomy. ,vol. 76, pp. 143- ,(1942)
Thomas Pk, The connective tissue of peripheral nerve: an electron microscope study. Journal of Anatomy. ,vol. 97, pp. 35- 44 ,(1963)
Paul C. Letourneau, Possible roles for cell-to-substratum adhesion in neuronal morphogenesis. Developmental Biology. ,vol. 44, pp. 77- 91 ,(1975) , 10.1016/0012-1606(75)90378-4
Roger J Keynes, William G Hopkins, Christopher L-H Huang, None, Regeneration of mouse peripheral nerves in degenerating skeletal muscle: guidance by residual muscle fibre basement membrane Brain Research. ,vol. 295, pp. 275- 281 ,(1984) , 10.1016/0006-8993(84)90976-4
Göran Lundborg, Lars B. Dahlin, Nils Danielsen, Richard H. Gelberman, Frank M. Longo, Henry C. Powell, Silvio Varon, Nerve regeneration in silicone chambers: Influence of gap length and of distal stump components Experimental Neurology. ,vol. 76, pp. 361- 375 ,(1982) , 10.1016/0014-4886(82)90215-1
M. A. Glasby, S. G. Gschmeissner, R. J. I. Hitchcock, C. L. -H. Huang, The dependence of nerve regeneration through muscle grafts in the rat on the availability and orientation of basement membrane. Journal of Neurocytology. ,vol. 15, pp. 497- 510 ,(1986) , 10.1007/BF01611732
James L Salzer, Richard P Bunge, None, Studies of Schwann cell proliferation. I. An analysis in tissue culture of proliferation during development, Wallerian degeneration, and direct injury. Journal of Cell Biology. ,vol. 84, pp. 739- 752 ,(1980) , 10.1083/JCB.84.3.739
David G. Kline, George J. Hayes, Arthur S. Morse, A COMPARATIVE STUDY OF RESPONSE OF SPECIES TO PERIPHERAL-NERVE INJURY. II. CRUSH AND SEVERANCE WITH PRIMARY SUTURE. Journal of Neurosurgery. ,vol. 21, pp. 980- 988 ,(1964) , 10.3171/JNS.1964.21.11.0980
P. K. Thomas, THE DEPOSITION OF COLLAGEN IN RELATION TO SCHWANN CELL BASEMENT MEMBRANE DURING PERIPHERAL NERVE REGENERATION. Journal of Cell Biology. ,vol. 23, pp. 375- 382 ,(1964) , 10.1083/JCB.23.2.375