Two descending nerve pathways activated by distension of guinea-pig small intestine.

摘要: 1. Intracellular recordings were made from myenteric neurones of the guinea-pig small intestine in preparations which had a synaptic input an orally situated segment intestine. 2. Excitatory potentials could be evoked most by distension attached intestinal segment. 3. It was possible to distinguish two distinct firing patterns response distension. A transient short latency discharge recorded some neurones. From others, persistent only after long (2-11 sec). 4. Distension segments inhibitory junction circular muscle layer followed excitatory both and longitudinal layers. 5. is suggested that may cause descending inhibition and, delay, excitation