Dengue and dengue hemorrhagic fever

摘要: Dengue fever, a very old disease, has reemerged in the past 20 years with an expanded geographic distribution of both viruses and mosquito vectors, increased epidemic activity, development hyperendemicity (the cocirculation multiple serotypes), emergence dengue hemorrhagic fever new regions. In 1998 this mosquito-borne disease is most important tropical infectious after malaria, estimated 100 million cases 500,000 25,000 deaths annually. The reasons for resurgence waning 20th century are complex not fully understood, but demographic, societal, public health infrastructure changes 30 have contributed greatly. This paper reviews changing epidemiology by region, natural history transmission cycles, clinical diagnosis serologic virologic laboratory diagnoses, pathogenesis, surveillance, prevention, control. A major challenge officials all areas world to devleop implement sustainable prevention control programs that will reverse trend emergent fever.