Bioassay‐guided Evaluation of Antinociceptive Properties and Chemical Variability of the Essential Oil of Hyptis fruticosa
作者： Clóvis R. P. Franco , Ângelo R. Antoniolli , Adriana G. Guimarães , Daniela M. Andrade , Hugo C. R. de Jesus
DOI: 10.1002/PTR.3455
关键词:
摘要: The composition of three samples essential oil (EO) extracted from the leaves and flowers Hyptis fruticosa (Lamiaceae) were investigated by GC/MS GC-FID. variability constituents biological activity evaluated in samples. Acetic acid-induced abdominal constrictions formalin-induced pain tests mice used for screening antinociceptive activity. possible antagonism oils or morphine (MOR) effects pretreatment with naloxone, showed no influence on action acetic writhing test. All examined presented sample obtained collected during vegetative growth stage, near Sao Cristovao at Sitio Tujubeba exhibited highest effect. same had a main percentage 1,8-cineole (18.70%). Nevertheless, location, significant difference (p < 0.05) response intensity first phase paw licking (100 mg/kg) possibly due to higher contents α-pinene (20.51%) β-pinene (13.64%). results provide evidence use H. traditional medicine practitioners management pain. Copyright © 2011 John Wiley & Sons, Ltd.
sci-hub.se 参考文章(27)
James D. Adams, Cecilia Garcia, Eric J. Lien, A comparison of chinese and american Indian (chumash) medicine. Evidence-based Complementary and Alternative Medicine. ,vol. 7, pp. 219- 225 ,(2010) , 10.1093/ECAM/NEM188
Marco Antonio Botelho, Vietla Satyanarayana Rao, Danusa Montenegro, Mary Anne Menezes Bandeira, Said Gonçalves Cruz Fonseca, Nadia Accioly Pinto Nogueira, Ronaldo Albuquerque Ribeiro, Gerly Anne Castro Brito, None, Effects of a herbal gel containing carvacrol and chalcones on alveolar bone resorption in rats on experimental periodontitis Phytotherapy Research. ,vol. 22, pp. 442- 449 ,(2008) , 10.1002/PTR.2325
L.J. Quintans-Júnior, T.T. Souza, B.S. Leite, N.M.N. Lessa, L.R. Bonjardim, M.R.V. Santos, P.B. Alves, A.F. Blank, A.R. Antoniolli, Phythochemical screening and anticonvulsant activity of Cymbopogon winterianus Jowitt (Poaceae) leaf essential oil in rodents. Phytomedicine. ,vol. 15, pp. 619- 624 ,(2008) , 10.1016/J.PHYMED.2007.09.018
Damião Pergentino de Sousa, Lucindo Quintans, Reinaldo Nóbrega de Almeida, Evolution of the Anticonvulsant Activity of α-Terpineol Pharmaceutical Biology. ,vol. 45, pp. 69- 70 ,(2007) , 10.1080/13880200601028388
Alejandra Rojas, Lourdes Hernandez, Rogelio Pereda-Miranda, Rachel Mata, Screening for antimicrobial activity of crude drug extracts and pure natural products from Mexican medicinal plants Journal of Ethnopharmacology. ,vol. 35, pp. 275- 283 ,(1992) , 10.1016/0378-8741(92)90025-M
Sônia Maria O. Costa, Telma Leda G. Lemos, Otília Deusdênial L. Pessoa, Claudia Pessoa, Raquel C. Montenegro, Raimundo Braz-Filho, Chemical constituents from Lippia sidoides and cytotoxic activity. Journal of Natural Products. ,vol. 64, pp. 792- 795 ,(2001) , 10.1021/NP0005917
F. A. Santos, V. S. N. Rao, Antiinflammatory and antinociceptive effects of 1,8-cineole a terpenoid oxide present in many plant essential oils. Phytotherapy Research. ,vol. 14, pp. 240- 244 ,(2000) , 10.1002/1099-1573(200006)14:4<240::AID-PTR573>3.0.CO;2-X
Charis Liapi, Georgios Anifantis, Ioanna Chinou, Angeliki Kourounakis, Stelios Theodosopoulos, Panagiota Galanopoulou, Antinociceptive Properties of 1,8-Cineole and β-Pinene, from the Essential Oil of Eucalyptus camaldulensis Leaves, in Rodents Planta Medica. ,vol. 73, pp. 1247- 1254 ,(2007) , 10.1055/S-2007-990224
ADAIR R. S. SANTOS, VALDIR C. FILHO, RIVALDO NIERO, ANA M. VIANA, FABIO N. MORENO, MARIA M. CAMPOS, ROSENDO A. YUNES, JOÃO B. CALIXTO, Analgesic Effects of Callus Culture Extracts from Selected Species of Phyllanthus in Mice Journal of Pharmacy and Pharmacology. ,vol. 46, pp. 755- 759 ,(2011) , 10.1111/J.2042-7158.1994.TB03897.X
M.A. Botelho, N.A.P. Nogueira, G.M. Bastos, S.G.C. Fonseca, T.L.G. Lemos, F.J.A. Matos, D. Montenegro, J. Heukelbach, V.S. Rao, G.A.C. Brito, Antimicrobial activity of the essential oil from Lippia sidoides, carvacrol and thymol against oral pathogens. Brazilian Journal of Medical and Biological Research. ,vol. 40, pp. 349- 356 ,(2007) , 10.1590/S0100-879X2007000300010