Trends in paediatric inpatient antibiotic therapy in a secondary care setting.

摘要: There is growing attention for antimicrobial stewardship in paediatrics. Currently, little known about secondary care antibiotic practice. We analysed trends time with respect to inpatient use a paediatric setting. Total consumption per year (2010–2015) and prescriptions urinary tract infection (UTI) lower respiratory (LRTI) were analysed. Variables total, antibiotic-specific, intravenous days of therapy (DOT/100PD) UTI/LRTI treatment type, route duration. Third-generation cephalosporin decreased (DOT/100PD 11.6 2011 vs. 5.1 2015; p < 0.001); antibiotics prescribed less often (p = 0.06). These findings confirmed the specific diseases: third-generation both UTI (93% 45%; p = 0.002) LRTI (14% 6%; p = 0.18); duration (UTI p = 0.02; p < 0.001). Median was 9.2 days 2008 6.6 2015 (p < 0.001); penicillin more narrow spectrum (p = 0.02). Conclusion: A decrease identified. significantly shorter spectrum. This could be explained by awareness interventions context stewardship. also feasible important non-tertiary wards.