ACTH, beta-endorphin, substance P, and corticotrophin releasing hormone in plasma and follicular fluid in hormonally stimulated menstrual cycles for in-vitro fertilization in the human.

摘要: Changes in plasma concentrations of ACTH, beta-endorphin (beta-EP) and cortisol have been found to be associated during the human menstrual cycle. hypothalamic levels gonadotrophin releasing hormone (GnRH), beta-EP substance P (SP) also with oestrous cycle rat. Therefore, an attempt was made measure activity corticotrophic axis SP by measuring blood follicular fluid beta-EP, corticotrophin (CRH) hormonal ovarian stimulation phase for in-vitro fertilization (IVF), a series 19 patients. At level, there no significant change over treatment days ACTH (P = 0.1550), 0.1137), or 0.5625). CRH not detectable days. In addition, neuropeptide between those women who became pregnant did 0.17 all). fluid, detectable, concentration three times higher than plasma, similar that plasma. There apparent correlation, however, from given patient. conclusion, absence changes suggests major stress component IVF occurrence pregnancy.