Immunohistochemical study of perforin and apoptosis stimulation fragment ligand (FasL)in active vitiligo.

作者: Akmal Saad Hassan , May Malek Kohil , Safinaz Salah Eldin Sayed , Sara Bahaa Mahmoud

DOI: 10.1007/S00403-020-02117-7

关键词:

摘要: … between epidermal and dermal perforin in perilesional skin. … perforin, as well as epidermal and dermal FasL in non-lesional skin. In conclusion, the significant expression of perforin and …

参考文章(25)
W. Westerhof, I. C. Le Poole, R. M. J. G. J. Van Den Wijngaard, P. K. Das, Presence of T cells and macrophages in inflammatory vitiligo skin parallels melanocyte disappearance American Journal of Pathology. ,vol. 148, pp. 1219- 1228 ,(1996)
S. You, Y.-H. Cho, J.-S. Byun, E.-C. Shin, Melanocyte-specific CD8+ T cells are associated with epidermal depigmentation in a novel mouse model of vitiligo Clinical and Experimental Immunology. ,vol. 174, pp. 38- 44 ,(2013) , 10.1111/CEI.12146
Jamie A Lopez, Olivia Susanto, Misty R Jenkins, Natalya Lukoyanova, Vivien R Sutton, Ruby HP Law, Angus Johnston, Catherina H Bird, Phillip I Bird, James C Whisstock, Joseph A Trapani, Helen R Saibil, Ilia Voskoboinik, None, Perforin forms transient pores on the target cell plasma membrane to facilitate rapid access of granzymes during killer cell attack Blood. ,vol. 121, pp. 2659- 2668 ,(2013) , 10.1182/BLOOD-2012-07-446146
M. D. Njoo, P. K. Das, J. D. Bos, W. Westerhof, Association of the Köbner phenomenon with disease activity and therapeutic responsiveness in vitiligo vulgaris. Archives of Dermatology. ,vol. 135, pp. 407- 413 ,(1999) , 10.1001/ARCHDERM.135.4.407
Carol L. Huang, James J. Nordlund, Raymond Boissy, Vitiligo: a manifestation of apoptosis? American Journal of Clinical Dermatology. ,vol. 3, pp. 301- 308 ,(2002) , 10.2165/00128071-200203050-00001
Frédérique-Anne Le Gal, Philippe Lefebvre, Jean-Christophe Deschemin, Muriel Andrieu, Jean-Gérard Guillet, Marie-Françoise Avril, Jacques Bosq, Martin-Xavier Dore, Direct evidence to support the role of antigen-specific CD8(+) T cells in melanoma-associated vitiligo. Journal of Investigative Dermatology. ,vol. 117, pp. 1464- 1470 ,(2001) , 10.1046/J.0022-202X.2001.01605.X
JILONG WU, MIAONI ZHOU, YINSHENG WAN, AIE XU, CD8+ T cells from vitiligo perilesional margins induce autologous melanocyte apoptosis. Molecular Medicine Reports. ,vol. 7, pp. 237- 241 ,(2013) , 10.3892/MMR.2012.1117
Flavia M.N. Pretti Aslanian, Rosangela A.M. Noé, Tullia Cuzzi, Absalom L. Filgueira, Abnormal histological findings in active vitiligo include the normal-appearing skin. Pigment Cell Research. ,vol. 20, pp. 144- 145 ,(2007) , 10.1111/J.1600-0749.2007.00366.X
Philippe Wehrli, Isabelle Viard, Roberto Bullani, Lars E. French, Jürg Tschopp, Death Receptors in Cutaneous Biology and Disease Journal of Investigative Dermatology. ,vol. 115, pp. 141- 148 ,(2000) , 10.1046/J.1523-1747.2000.00037.X
Shih-Chi Su, Wen-Hung Chung, Cytotoxic Proteins and Therapeutic Targets in Severe Cutaneous Adverse Reactions Toxins. ,vol. 6, pp. 194- 210 ,(2014) , 10.3390/TOXINS6010194