Reliability and Validity of Four Alternative Definitions of Rapid-Cycling Bipolar Disorder

摘要: OBJECTIVE: This study tested the reliability and validity of four definitions rapid cycling. METHOD: Two trained psychiatrists, using Schedule for Affective Disorders Schizophrenia, independently assessed 210 patients with bipolar disorder. They checked whether each patient met cycling: one consistent DSM-IV criteria, waiving criteria duration affective episodes, such requiring at least switch from mania to depression or vice versa during reference year, 8 weeks fully symptomatic illness year. The interrater was calculated by Cohen’s kappa statistic. Patients who definition according both psychiatrists were compared those did not meet any (nonrapid-cycling group) on demographic clinical variables. All followed up 1 RESULTS: Kappa values 0.93, 0.73, 0.75, and...