摘要: Posttranslational modifications such as palmitoylation have the ability to modulate protein localization and function. The reversible addition of fatty acid palmitate proteins has been known occur in neurons for a considerable amount time noticed be particular importance at synapses. In this issue Neuron, Huang et al. Fukata describe their studies palmitoyl transferases how these enzymes specifically catalyze modification number synaptic proteins, including postsynaptic scaffolding PSD-95.