Prescription of nonsteroidal anti-inflammatory drugs for elderly people in Alberta

摘要: OBJECTIVE: To examine the extent prescribed nonsteroidal anti-inflammatory drugs (NSAIDs) are used by elderly people in Alberta as well degree of concurrent use multiple NSAIDs, peptic ulcer medications and certain known to have clinically significant adverse interactions with NSAIDs. DESIGN: Retrospective analysis Blue Cross database. SETTING: Alberta. PATIENTS: All 65 years age older using subsidized drug benefit plan for whom prescription claims were submitted reimbursement between Jan. 1 June 30, 1991. OUTCOME MEASURES: Number who received one or more prescriptions rates prescribing potential NSAIDs among NSAID users non-NSAID users, rate than concurrently. RESULTS: Of Albertan population over 61,601 (26.7%) at least an during study period. In decreasing order, five most commonly acetylsalicylic acid, diclofenac, naproxen, indomethacin ibuprofen. The total cost therapy was $5,415,974. 25.8% also a medication, compared 10.5% users. There relation increasing number likelihood receiving medication. Those likely been coumarin anticoagulants, diuretics, angiotensin-converting-enzyme inhibitors, beta-blockers, oral corticosteroids, methotrexate lithium, all which possible A 2,631 had two filled on same day. CONCLUSIONS: frequently associated increased medication that could Additional is required evaluate appropriateness patients, determine actual patient consumption these medications, document true prevalence formulate educational strategies reach physicians this information.