Ultrahigh speed spectral-domain optical coherence microscopy.

作者: Hsiang-Chieh Lee , Jonathan J. Liu , Yuri Sheikine , Aaron D. Aguirre , James L. Connolly

DOI: 10.1364/BOE.4.001236

关键词:

摘要: We demonstrate a compact, ultrahigh speed spectral-domain optical coherence microscopy (SD-OCM) system for multiscale imaging of specimens at 840 nm. Using high 512-pixel line scan camera, an 210,000 A-scans per second was demonstrated. Interchangeable water immersion objectives with magnifications 10×, 20×, and 40× provided co-registered en face cellular-resolution over several size scales. Volumetric OCM data sets images were demonstrated on both normal pathological human colon kidney ex vivo axial resolution ~4.2 µm, transverse resolutions ~2.9 µm (10×), ~1.7 (20×), ~1.1 (40×) in tissue. In addition, acquired numerical aperture extended field-of-view (FOV) using image mosaicking. Comparison between among different demonstrated, which promises to help the design evaluation performance Fourier domain systems regimes.

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