Comparison and Critique of Government Regulations for Behavioral Teratology

摘要: Behavioral teratogenesis is a well-established phenomenon in experimental animals (Barlow & Sullivan, 1975; Hutchings, 1983; Vorhees Butcher, 1982). This fact alone should probably have been enough to trigger government agencies responsible for the protection of public health and environment incorporate this new aspect risk into regulations safety assessment. Unfortunately, world seldom operates so simply. Health environmental react evidence derived exclusively from animal research, behavioral teratology received modest attention until several human teratogens were identified (Hattan, Henry, Montgomery, Bleiberg, Rulis, Bolger, 1983). identification began with prenatal methylmercury poisoning congenital Minamata disease (Reuhl Chang, 1979; Takeuchi, Eto, 1979), followed by fetal alcohol syndrome (Jones Smith, 1973; Jones, Ulleland, Streissguth, 1973), hydantoin (Hanson 1975), trimethadione (Feldman, Weaver, Lovrien, 1977; German, Kowal, Ehlers, 1970; Zackai, Mellman, Neiderer, Hanson, neonatal withdrawal longer-term effects produced narcotic addiction (Kandall, Kandall, Albin, Gartner, Lee, Eidelman, Lowinson, Lodge, Wilson, Desmond, Verniaud, 1973).