Weissella confusa bacteremia in a liver transplant patient with hepatic artery thrombosis.

作者: N.P. Harlan , R.R. Kempker , S.M. Parekh , E.M. Burd , D.T. Kuhar

DOI: 10.1111/J.1399-3062.2010.00579.X

关键词:

摘要: A 54-year-old man with a history of nonalcoholic steatohepatitis and hepatocellular carcinoma presented 2 months after an orthotopic liver transplant fever abdominal pain. Two weeks earlier, he had hepatic artery thrombosis biliary stricture, for which stent were placed. Laboratory workup was significant leukocyte count 7800/mcL 92% segmented neutrophils, hemoglobin 9.4 g/dL, alanine aminotransferase 98 U/L, aspartate 72 alkaline phosphatase 358 albumin 2.8 mg/dL, total bilirubin 1.6 mg/dL. computed tomography scan the abdomen pelvis revealed multiple small fluid collections in consistent bilomas, angiogram showed complete occlusion common artery. sets blood cultures positive organism initially identified by MicroScan(®) analysis as α-hemolytic Streptococcus species that resistant to vancomycin. Further testing confirmed Weissella confusa days later. W. is gram-positive coccobacillus may be misidentified Lactobacillus when cultured. It commonly found sewage, carrots, sugar cane, fermented foods, intestinal flora. Although only 4 cases clinical infection have been described previously, has isolated from stool patients, underreported cause owing improper identification. As it can these immunosuppressed hosts, identification this paramount because vancomycin resistant, incorrect could lead antimicrobial selection ultimately worsened patient morbidity or mortality.

参考文章(11)
M Green, K Barbadora, M Michaels, Recovery of vancomycin-resistant gram-positive cocci from pediatric liver transplant recipients. Journal of Clinical Microbiology. ,vol. 29, pp. 2503- 2506 ,(1991) , 10.1128/JCM.29.11.2503-2506.1991
M Green, R M Wadowsky, K Barbadora, Recovery of vancomycin-resistant gram-positive cocci from children. Journal of Clinical Microbiology. ,vol. 28, pp. 484- 488 ,(1990) , 10.1128/JCM.28.3.484-488.1990
T G Sokolova, J M González, N A Kostrikina, N A Chernyh, T P Tourova, C Kato, E A Bonch-Osmolovskaya, F T Robb, Carboxydobrachium pacificum gen. nov., sp. nov., a new anaerobic, thermophilic, CO-utilizing marine bacterium from Okinawa Trough. International Journal of Systematic and Evolutionary Microbiology. ,vol. 51, pp. 141- 149 ,(2001) , 10.1099/00207713-51-1-141
W J Riebel, J A Washington, Clinical and microbiologic characteristics of pediococci. Journal of Clinical Microbiology. ,vol. 28, pp. 1348- 1355 ,(1990) , 10.1128/JCM.28.6.1348-1355.1990
C E Bantar, S Relloso, F R Castell, J Smayevsky, H M Bianchini, Abscess caused by vancomycin-resistant Lactobacillus confusus. Journal of Clinical Microbiology. ,vol. 29, pp. 2063- 2064 ,(1991) , 10.1128/JCM.29.9.2063-2064.1991
R. Patel, F. R. Cockerill, M. K. Porayko, D. R. Osmon, D. M. Ilstrup, M. R. Keating, Lactobacillemia in Liver Transplant Patients Clinical Infectious Diseases. ,vol. 18, pp. 207- 212 ,(1994) , 10.1093/CLINIDS/18.2.207
Pavel Švec, Alena Ševčíková, Ivo Sedláček, Jana Bednářová, Cindy Snauwaert, Karen Lefebvre, Peter Vandamme, Marc Vancanneyt, Identification of lactic acid bacteria isolated from human blood cultures Fems Immunology and Medical Microbiology. ,vol. 49, pp. 192- 196 ,(2007) , 10.1111/J.1574-695X.2006.00199.X
Jeong Hwan Shin, Doo Il Kim, Hye Ran Kim, Dong Soo Kim, Joong-Ki Kook, Jeong Nyeo Lee, Severe infective endocarditis of native valves caused by Weissella confusa detected incidentally on echocardiography. Journal of Infection. ,vol. 54, ,(2007) , 10.1016/J.JINF.2006.09.009
Carlos Vay, Roxana Cittadini, Claudia Barberis, Carlos Hernán Rodríguez, Herminia Perez Martínez, Fabiana Genero, Angela Famiglietti, Antimicrobial susceptibility of non-enterococcal intrinsic glycopeptide-resistant Gram-positive organisms Diagnostic Microbiology and Infectious Disease. ,vol. 57, pp. 183- 188 ,(2007) , 10.1016/J.DIAGMICROBIO.2006.08.014
K Johanna Björkroth, Ulrich Schillinger, Rolf Geisen, Norbert Weiss, Bart Hoste, Wilhelm H Holzapfel, Hannu J Korkeala, Peter Vandamme, Taxonomic study of Weissella confusa and description of Weissella cibaria sp. nov., detected in food and clinical samples International Journal of Systematic and Evolutionary Microbiology. ,vol. 52, pp. 141- 148 ,(2002) , 10.1099/00207713-52-1-141