Reactive Oxygen Species in Inflammation and Tissue Injury
作者： Manish Mittal , Mohammad Rizwan Siddiqui , Khiem Tran , Sekhar P. Reddy , Asrar B. Malik
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摘要: Abstract Reactive oxygen species (ROS) are key signaling molecules that play an important role in the progression of inflammatory disorders. An enhanced ROS generation by polymorphonuclear neutrophils (PMNs) at site inflammation causes endothelial dysfunction and tissue injury. The vascular endothelium plays passage macromolecules cells from blood to tissue. Under conditions, oxidative stress produced PMNs leads opening inter-endothelial junctions promotes migration across barrier. migrated not only help clearance pathogens foreign particles but also lead current review compiles past research area with particular emphasis on stress-mediated mechanisms involved
sci-hub.se 参考文章(476)
Siegfried Hekimi, Dantong Wang, Danielle Malo, Elevated Mitochondrial Reactive Oxygen Species Generation Affects the Immune Response via Hypoxia-Inducible Factor-1α in Long-Lived Mclk1+/− Mouse Mutants Journal of Immunology. ,vol. 184, pp. 582- 590 ,(2010) , 10.4049/JIMMUNOL.0902352
E Graf, J R Mahoney, R G Bryant, J W Eaton, Iron-catalyzed hydroxyl radical formation. Stringent requirement for free iron coordination site. Journal of Biological Chemistry. ,vol. 259, pp. 3620- 3624 ,(1984) , 10.1016/S0021-9258(17)43139-5
Guido Kroemer, John C. Reed, Mitochondrial control of cell death Nature Medicine. ,vol. 6, pp. 513- 519 ,(2000) , 10.1038/74994
J A Thomas, R B Johnston, K Rokutan, Phagocytosis and stimulation of the respiratory burst by phorbol diester initiate S-thiolation of specific proteins in macrophages. Journal of Immunology. ,vol. 147, pp. 260- 264 ,(1991)
Hye Sun Park, Hye Young Jung, Eun Young Park, Jaesang Kim, Won Jae Lee, Yun Soo Bae, Cutting Edge: Direct Interaction of TLR4 with NAD(P)H Oxidase 4 Isozyme Is Essential for Lipopolysaccharide-Induced Production of Reactive Oxygen Species and Activation of NF-κB Journal of Immunology. ,vol. 173, pp. 3589- 3593 ,(2004) , 10.4049/JIMMUNOL.173.6.3589
Bernard M. Babior, NADPH Oxidase: An Update Blood. ,vol. 93, pp. 1464- 1476 ,(1999) , 10.1182/BLOOD.V93.5.1464
G A Visner, W C Dougall, J M Wilson, I A Burr, H S Nick, Regulation of manganese superoxide dismutase by lipopolysaccharide, interleukin-1, and tumor necrosis factor. Role in the acute inflammatory response. Journal of Biological Chemistry. ,vol. 265, pp. 2856- 2864 ,(1990) , 10.1016/S0021-9258(19)39880-1
Heather E. Matheny, Tracy L. Deem, Joan M. Cook-Mills, Lymphocyte Migration Through Monolayers of Endothelial Cell Lines Involves VCAM-1 Signaling Via Endothelial Cell NADPH Oxidase The Journal of Immunology. ,vol. 164, pp. 6550- 6559 ,(2000) , 10.4049/JIMMUNOL.164.12.6550
Christopher Hwang, Harvey F. Lodish, Anthony J. Sinskey, [18] Measurement of glutathione redox state in cytosol and secretory pathway of cultured cells Methods in Enzymology. ,vol. 251, pp. 212- 221 ,(1995) , 10.1016/0076-6879(95)51123-7
R.P. McEver, K.L. Moore, D.E. Lyons, R.D. Cummings, S.F. Eaton, H.S. Lichenstein, The P-selectin glycoprotein ligand from human neutrophils displays sialylated, fucosylated, O-linked poly-N-acetyllactosamine. Journal of Biological Chemistry. ,vol. 269, pp. 23318- 23327 ,(1994) , 10.1016/S0021-9258(17)31656-3