A mathematical model of chemoreflex responses to hypercapnic stimuli.

作者: William S. Yamamoto , Polly S. Yamamoto

DOI: 10.1016/0010-4809(79)90007-7

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摘要: Abstract A mathematical model of the carotid body chemoreceptor reflex was constructed using first-order recursive digital filter expressions for excitatory state, neural impulses from non-negative states, and a switched system central pathways. The switching between filters employed to represent apparent alteration in effect afferent arriving at different phases respiratory cycle. equations were programmed computation. When connected subsidiary representing chest drive, principal features CO 2 responses body, nerve, pathways as reported experiments on cat could be simulated with single set parameters. is suitable integration into larger models investigation control ventilation.

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