Associations between indicators of livestock farming intensity and incidence of human Shiga toxin-producing Escherichia coli infection.

摘要: The impact of livestock farming on the incidence human Shiga toxin-producing Escherichia coli (STEC) infection was assessed by using several density indicators (LDI) that were generated in a systematic approach. A total 80 LDI considered suitable proxy measures for density. Multivariate Poisson regression identified as having significant spatial association with STEC infection. strongest associations ratio beef cattle number to population and application manure surface agricultural land solid spreader liquid showed. This study demonstrates value approach identifying other predictors disease. nfection is associated spectrum illnesses including watery diarrhea, bloody hemolytic uremic syndrome, potentially fatal condition characterized acute renal failure (1). Although variety E. serotypes have been illness, most important among these O157:H7. Cattle are principal reservoir organisms. Important sources include consumption undercooked hamburger contaminated food products direct or indirect contact infected persons (2-4). Recent studies suggest exposure potential (2,3). Among this evidence finding Michel et al. higher rural areas than urban Ontario, Canada. By analysis, investigators demonstrated strong between density, expressed per hectare. Potential routes settings (2,5), raw milk (2,4), contamination well water runoff (6,7), locally produced products(8). taken (3) analysis at high risk elucidating factors. objective present develop creating evaluating (livestock indicators, LDI) means those best suited assessing activities Methods