Autophagy as the cell survival in response to a microsporidian infection of the midgut epithelium of Isohypsibius granulifer granulifer (Eutardigrada: Hypsibiidae)

摘要: The midgut epithelial cells of many invertebrates may possess microorganisms which act as symbionts or pathogens (bacteria, microsporidia, viruses). During our previous studies on Isohypsibius granulifer Thulin, 1928 (Tardigrada, Eutardigrada), examined alterations the epithelium during oogenesis, we found that some specimens were infected with microsporidia. All stages occurred in cytoplasm digestive I. g. granulifer microsporidia: meronts, sporonts, sporoblasts, and spores. was rich mitochondria, cisterns rough endoplasmic reticulum (RER), Golgi complexes. Autophagy dorsal much more intensive comparison noninfected specimens. Membranes phagophores surrounded forming autophagosomes. These latter structures fused lysosomes autolysosomes residual bodies appeared. Neither glycogen granules nor droplets varying electron density, accumulated vitellogenesis choriogenesis, appeared individuals While takes part specimens, are involved process autophagy a survival strategy.