Distinctive neuropsychological profiles differentiate patients with functional memory disorder from patients with amnestic-mild cognitive impairment.

摘要: OBJECTIVES: Patients with functional memory disorder (FMD) report significant failures in everyday life. Differentiating these patients from those difficulties due to early stage neurodegenerative conditions is clinically challenging. The current study explored whether distinctive neuropsychological profiles could be established, suitable differentiate FMD healthy individuals and experiencing amnestic mild cognitive impairment (a-MCI). METHODS: a clinical diagnosis of were compared a-MCI, matched controls on several tests assessing different functions. established mood disorders excluded. a-MCI broadly comparable the level their subjective complaints as assessed by interview. RESULTS: profile patients, although they expressed attention concerns during interview was distinct [semantic fluency, age acquisition (AoA) analysis semantic verbal non-verbal memory]. did not differ significantly controls, but scores letter fluency digit cancellation tasks indicating possible sub-threshold deficit tasks. CONCLUSION: Whilst are common within population, no objective detected, even sensitive battery designed detect subtle deficits caused an brain disease. This indicates that can successfully differentiated decline characterising profile.