Quality of Life Analyses in a Clinical Trial of DPPE (tesmilifene) Plus Doxorubicin Versus Doxorubicin in Patients with Advanced or Metastatic Breast Cancer: NCIC CTG Trial MA.19
作者： Jianhua Liu , Dongsheng Tu , Janet Dancey , Leonard Reyno , Kathleen I. Pritchard
DOI: 10.1007/S10549-006-9257-1
关键词:
摘要: Background DPPE (tesmilifene) plus doxorubicin (DOX) demonstrated a significant improvement in survival versus DOX phase III clinical trial advanced breast cancer. However, DPPE is associated with unusual toxicity the form of hallucinations, nausea and vomiting which were anticipated to impact on short-term quality life (QOL).
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