Somatic cell reprogrammed by oocyte: process and barricade
作者： LiBing Ma , XiaoYing He , FengMei Wang , Teng Cheng , XiYu Liu
DOI: 10.1080/19768354.2014.927397
关键词:
摘要: Somatic cell nuclear transfer (SCNT) is a technology in which somatic nucleus transferred into the cytoplasm of matured oocyte – reconstructed embryos have capacity to develop term. Why cells can be reprogrammed by oocytes answer for this question must exist oocytes. In review, totipotent characters were discussed, may confer with reprogram nucleus. Moreover, procedure SCNT also makes possibility Compared fertilized embryos, derived from exhibit low developmental ability; barricades reprogramming process and their possible reasons discussed. This review maybe benefit mechanism research make contribution improving efficiency technology.
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