Novel piperidine derivatives for use in the treatment of chemokine mediated disease states
作者： Brian Springthorpe , Matthew Perry , Christopher Luckhurst
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摘要: Disclosed are compounds of formula (I), wherein: X is CH2, C(O), O, S, S(O), S(O)2 or NR3, Y a bond, optionally substituted alkylene, phenylene heterocyclylene, Z CO2Rb, NHS(O)2CF3, S(O)2OH, OCH2CO2Rb tetrazolyl, R1 and R2 independently H, alkyl, aryl heterocyclyl, Ra Rb when heterocyclyl may be alkylene forming ring R2, Rc H hydroxy. The used for the manufacture medicaments treatment chemokine mediated disease states.
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