Simultaneous contactless conductivity detection and UV detection for the study of separation of tamsulosin enantiomers in discontinuous electrolyte systems by CE.
作者： Jan Petr , Vítězslav Maier , Jana Horáková , Juraj Ševčík
关键词:
摘要: This work shows the potential of using discontinuous electrolyte systems for separation tamsulosin enantiomers by CE. Sulfated beta-cyclodextrin was used as a chiral selector. In acidic electrolytes, sulfated migrates an anion and analyte (tamsulosin) cation. Due to this, four experimental arrangements were proposed. These differ in composition electrolytes inlet compartment, capillary outlet compartment. The acetate buffers with sodium Tris counterions studied. Simultaneous contactless conductivity detection UV study mechanism these systems. Mobilities calculation time when through BGE zone simulation program Simul 4.0 calculations concentration profiles components dependent on separation. enantioseparation suggested.
sci-hub.se 参考文章(51)
Bezhan Chankvetadze, Capillary Electrophoresis in Chiral Analysis ,(1997)
Pavel Kubáň, Peter C. Hauser, Contactless Conductivity Detection in Capillary Electrophoresis: A Review Electroanalysis. ,vol. 16, pp. 2009- 2021 ,(2004) , 10.1002/ELAN.200403125
Christine. Schwer, Bohuslav. Gas, Friedrich. Lottspeich, Ernst. Kenndler, Computer simulation and experimental evaluation of on-column sample preconcentration in capillary zone electrophoresis by discontinuous buffer systems Analytical Chemistry. ,vol. 65, pp. 2108- 2115 ,(1993) , 10.1021/AC00063A030
Xavier Subirats, Simo P. Porras, Martí Rosés, Ernst Kenndler, Nitromethane as solvent in capillary electrophoresis. Journal of Chromatography A. ,vol. 1079, pp. 246- 253 ,(2005) , 10.1016/J.CHROMA.2005.02.072
Eva Tesařová, Juraj Ševčík, Bohuslav Gaš, Daniel W. Armstrong, Effects of partial/asymmetrical filling of micelles and chiral selectors on capillary electrophoresis enantiomeric separation: generation of a gradient. Electrophoresis. ,vol. 25, pp. 2693- 2700 ,(2004) , 10.1002/ELPS.200405972
Jan Muzikár, Tom van de Goor, Bohuslav Gaš, Ernst Kenndler, Extension of the application range of UV-absorbing organic solvents in capillary electrophoresis by the use of a contactless conductivity detector. Journal of Chromatography A. ,vol. 924, pp. 147- 154 ,(2001) , 10.1016/S0021-9673(01)00853-6
B. Gaš, M. Demjaněnko, J. Vacík, High-frequency contactless conductivity detection in isotachophoresis Journal of Chromatography A. ,vol. 192, pp. 253- 257 ,(1980) , 10.1016/S0021-9673(80)80001-X
Petr Barták, Petr Bednář, Lubomı́r Kubáček, Zdeněk Stránský, Advanced statistical evaluation of complex formation constant from electrophoretic data Analytica Chimica Acta. ,vol. 407, pp. 327- 336 ,(2000) , 10.1016/S0003-2670(99)00785-0
Philip Britz-McKibbin, Shigeru Terabe, On-line preconcentration strategies for trace analysis of metabolites by capillary electrophoresis Journal of Chromatography A. ,vol. 1000, pp. 917- 934 ,(2003) , 10.1016/S0021-9673(03)00502-8
Izabella Surowiec, Isabella Kaml, Ernst Kenndler, Analysis of drying oils used as binding media for objects of art by capillary electrophoresis with indirect UV and conductivity detection Journal of Chromatography A. ,vol. 1024, pp. 245- 254 ,(2004) , 10.1016/J.CHROMA.2003.10.065