Enzyme-responsive polyion complex (PIC) nanoparticles for the targeted delivery of antimicrobial polymers
作者： Ignacio Insua , Evangelos Liamas , Zhenyu Zhang , Anna F. A. Peacock , Anne Marie Krachler
DOI: 10.1039/C6PY00146G
关键词:
摘要: Here we present new enzyme-responsive polyion complex (PIC) nanoparticles prepared from antimicrobial poly(ethylene imine) and an anionic enzyme-responsive peptide targetingPseudomonas aeruginosa's elastase.
rsc.org
sci-hub.se 参考文章(36)
Iria Louzao, Cheng Sui, Klaus Winzer, Francisco Fernandez-Trillo, Cameron Alexander, Cationic polymer mediated bacterial clustering: Cell-adhesive properties of homo- and copolymers European Journal of Pharmaceutics and Biopharmaceutics. ,vol. 95, pp. 47- 62 ,(2015) , 10.1016/J.EJPB.2015.05.026
Neil D. Rawlings, Alan J. Barrett, J. F. Woessner, Handbook of proteolytic enzymes Elsevier Academic Press. ,(1998)
Victor W.L. Ng, Julian M.W. Chan, Haritz Sardon, Robert J. Ono, Jeannette M. García, Yi Yan Yang, James L. Hedrick, Antimicrobial hydrogels: a new weapon in the arsenal against multidrug-resistant infections. Advanced Drug Delivery Reviews. ,vol. 78, pp. 46- 62 ,(2014) , 10.1016/J.ADDR.2014.10.028
Mahmoud Soliman, Stephanie Allen, Martyn C. Davies, Cameron Alexander, Responsive polyelectrolyte complexes for triggered release of nucleic acid therapeutics. Chemical Communications. ,vol. 46, pp. 5421- 5433 ,(2010) , 10.1039/C0CC00794C
T. Blessing, J.-S. Remy, J.-P. Behr, Monomolecular collapse of plasmid DNA into stable virus-like particles Proceedings of the National Academy of Sciences of the United States of America. ,vol. 95, pp. 1427- 1431 ,(1998) , 10.1073/PNAS.95.4.1427
Elena B.M. Breidenstein, César de la Fuente-Núñez, Robert E.W. Hancock, Pseudomonas aeruginosa: all roads lead to resistance Trends in Microbiology. ,vol. 19, pp. 419- 426 ,(2011) , 10.1016/J.TIM.2011.04.005
Brad Spellberg, John G. Bartlett, David N. Gilbert, The Future of Antibiotics and Resistance New England Journal of Medicine. ,vol. 368, pp. 299- 302 ,(2013) , 10.1056/NEJMP1215093
Robert E W Hancock, Hans-Georg Sahl, Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies. Nature Biotechnology. ,vol. 24, pp. 1551- 1557 ,(2006) , 10.1038/NBT1267
Karyn Hede, Antibiotic resistance: An infectious arms race Nature. ,vol. 509, pp. S2- S3 ,(2014) , 10.1038/509S2A
Bengt Wretlind, Olǵerts R. Pavlovskis, Pseudomonas aeruginosa elastase and its role in pseudomonas infections Clinical Infectious Diseases. ,vol. 5, ,(1983) , 10.1093/CLINIDS/5.SUPPLEMENT_5.S998