Systematic classification of melanoma cells by phenotype-specific gene expression mapping.

作者: Daniel S. Widmer , Phil F. Cheng , Ossia M. Eichhoff , Benedetta C. Belloni , Marie C. Zipser

DOI: 10.1111/J.1755-148X.2012.00986.X

关键词:

摘要: … Specifically, we noted that MAP kinase inhibition of proliferative phenotype cells induced the acquisition of invasive phenotype characteristics, which would revert upon removal of the …

参考文章(48)
Robert Folberg, Zarema Arbieva, Jonas Moses, Amin Hayee, Tone Sandal, ShriHari Kadkol, Amy Y. Lin, Klara Valyi-Nagy, Suman Setty, Lu Leach, Patricia Chévez-Barrios, Peter Larsen, Dibyen Majumdar, Jacob Pe'er, Andrew J. Maniotis, Tumor Cell Plasticity in Uveal Melanoma: Microenvironment Directed Dampening of the Invasive and Metastatic Genotype and Phenotype Accompanies the Generation of Vasculogenic Mimicry Patterns American Journal of Pathology. ,vol. 169, pp. 1376- 1389 ,(2006) , 10.2353/AJPATH.2006.060223
Delphine Javelaud, Vasileia-Ismini Alexaki, Marie-Jeanne Pierrat, Keith S. Hoek, Sylviane Dennler, Leon Van Kempen, Corine Bertolotto, Robert Ballotti, Simon Saule, Véronique Delmas, Alain Mauviel, GLI2 and M-MITF transcription factors control exclusive gene expression programs and inversely regulate invasion in human melanoma cells. Pigment Cell & Melanoma Research. ,vol. 24, pp. 932- 943 ,(2011) , 10.1111/J.1755-148X.2011.00893.X
Marie C. Zipser, Ossia M. Eichhoff, Daniel S. Widmer, Natalie C. Schlegel, Nicola L. Schoenewolf, Darrin Stuart, Weihua Liu, Humphrey Gardner, Paul D. Smith, Paolo Nuciforo, Reinhard Dummer, Keith S. Hoek, A proliferative melanoma cell phenotype is responsive to RAF/MEK inhibition independent of BRAF mutation status. Pigment Cell & Melanoma Research. ,vol. 24, pp. 326- 333 ,(2011) , 10.1111/J.1755-148X.2010.00823.X
Ossia M. Eichhoff, Ashani Weeraratna, Marie C. Zipser, Laurence Denat, Daniel S. Widmer, Mai Xu, Lydia Kriegl, Thomas Kirchner, Lionel Larue, Reinhard Dummer, Keith S. Hoek, Differential LEF1 and TCF4 expression is involved in melanoma cell phenotype switching. Pigment Cell & Melanoma Research. ,vol. 24, pp. 631- 642 ,(2011) , 10.1111/J.1755-148X.2011.00871.X
Keith S. Hoek, Colin R. Goding, Cancer stem cells versus phenotype-switching in melanoma. Pigment Cell & Melanoma Research. ,vol. 23, pp. 746- 759 ,(2010) , 10.1111/J.1755-148X.2010.00757.X
Daniel Yekutieli, Yoav Benjamini, THE CONTROL OF THE FALSE DISCOVERY RATE IN MULTIPLE TESTING UNDER DEPENDENCY Annals of Statistics. ,vol. 29, pp. 1165- 1188 ,(2001) , 10.1214/AOS/1013699998
M. Bittner, P. Meltzer, Y. Chen, Y. Jiang, E. Seftor, M. Hendrix, M. Radmacher, R. Simon, Z. Yakhini, A. Ben-Dor, N. Sampas, E. Dougherty, E. Wang, F. Marincola, C. Gooden, J. Lueders, A. Glatfelter, P. Pollock, J. Carpten, E. Gillanders, D. Leja, K. Dietrich, C. Beaudry, M. Berens, D. Alberts, V. Sondak, N. Hayward, J. Trent, Molecular classification of cutaneous malignant melanoma by gene expression profiling Nature. ,vol. 406, pp. 536- 540 ,(2000) , 10.1038/35020115
Gideon Bollag, Peter Hirth, James Tsai, Jiazhong Zhang, Prabha N. Ibrahim, Hanna Cho, Wayne Spevak, Chao Zhang, Ying Zhang, Gaston Habets, Elizabeth A. Burton, Bernice Wong, Garson Tsang, Brian L. West, Ben Powell, Rafe Shellooe, Adhirai Marimuthu, Hoa Nguyen, Kam Y. J. Zhang, Dean R. Artis, Joseph Schlessinger, Fei Su, Brian Higgins, Raman Iyer, Kurt D’Andrea, Astrid Koehler, Michael Stumm, Paul S. Lin, Richard J. Lee, Joseph Grippo, Igor Puzanov, Kevin B. Kim, Antoni Ribas, Grant A. McArthur, Jeffrey A. Sosman, Paul B. Chapman, Keith T. Flaherty, Xiaowei Xu, Katherine L. Nathanson, Keith Nolop, Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF -mutant melanoma Nature. ,vol. 467, pp. 596- 599 ,(2010) , 10.1038/NATURE09454
Sophie Pinner, Peter Jordan, Kirsty Sharrock, Laura Bazley, Lucy Collinson, Richard Marais, Elise Bonvin, Colin Goding, Erik Sahai, None, Intravital Imaging Reveals Transient Changes in Pigment Production and Brn2 Expression during Metastatic Melanoma Dissemination Cancer Research. ,vol. 69, pp. 7969- 7977 ,(2009) , 10.1158/0008-5472.CAN-09-0781
Yoko Ueno, Hiroaki Sakurai, Satoshi Tsunoda, Min-Kyung Choo, Mitsuhiro Matsuo, Keiichi Koizumi, Ikuo Saiki, Heregulin-induced activation of ErbB3 by EGFR tyrosine kinase activity promotes tumor growth and metastasis in melanoma cells International Journal of Cancer. ,vol. 123, pp. 340- 347 ,(2008) , 10.1002/IJC.23465