作者: Kasumi Ishida , Junji Matsuo , Yoshimasa Yamamoto , Hiroyuki Yamaguchi
DOI: 10.1186/S12866-014-0330-3
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摘要: Background Pathogenic chlamydiae are obligate intracellular pathogens and have adapted successfully to human cells, causing sexually transmitted diseases or pneumonia. Chlamydial outer protein N (CopN) is likely a critical effector secreted by the type III secretion system in chlamydiae, which manipulates host cells. However, mechanisms of its action remain be clarified. In this work, we aimed identify previously unidentified CopN target