Chlamydia pneumoniae effector chlamydial outer protein N sequesters fructose bisphosphate aldolase A, providing a benefit to bacterial growth

作者: Kasumi Ishida , Junji Matsuo , Yoshimasa Yamamoto , Hiroyuki Yamaguchi

DOI: 10.1186/S12866-014-0330-3

关键词:

摘要: Background Pathogenic chlamydiae are obligate intracellular pathogens and have adapted successfully to human cells, causing sexually transmitted diseases or pneumonia. Chlamydial outer protein N (CopN) is likely a critical effector secreted by the type III secretion system in chlamydiae, which manipulates host cells. However, mechanisms of its action remain be clarified. In this work, we aimed identify previously unidentified CopN target

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