Renal vasculitis in Japan and the UK - are there differences in epidemiology and clinical phenotype?

摘要: Background. The epidemiology of renal vasculitis in different populations is poorly understood. A recent study fromJapansuggeststhatwhilsttheoverallincidenceissimilar to that reported from Europe, the clinical phenotype different, with Wegener’s granulomatosis being very much less common. aim this was compare incidence UK data a Japanese population. Methods. Incident patients were identified prospectively between 2000 and 2004 well-defined case notes reviewed features extracted. Classification granulomatosis, microscopic polyangiitis Churg Strauss syndrome performed using predetermined algorithm. Inclusion criteria (i) new or without histological confirmation, (ii) involvement (iii) positive serology for antineutrophil cytoplasmic antibody (ANCA). Results. We 27 cases (Wegener’sgranulomatosis13,microscopicpolyangiitis11, 3) fulfilling definition. overall average age 63.5 years which than those patients. annual 12.2/million similar Japan. 5.8/million,microscopicpolyangiitis4.9/millionandChurg 1.4/million. ENT neurological common No