CHARACTERISATION AND EXPRESSION OF A STAGE-REGULATED GENE OF LEISHMANIA MAJOR

作者: Fahimeh Nourbakhsh , Silvia RB Uliana , Deborah F Smith , None

DOI: 10.1016/0166-6851(95)02559-6

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摘要: This paper describes the isolation and characterisation of meta 1 gene from Leishmania major, that is expressed predominantly in infective metacyclic parasites. The termini major 2-kb transcript derived this have been mapped polypyrimidine sequences implicated RNA processing located flanking regions. conserved both Old New World species codes for a putative protein 112 amino acids. Antibodies raised against recombinant open reading frame recognise an 11.5-kDa cell lysates molecule localises to region flagellar pocket by indirect immunofluorescence.

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